Dysport vs Botox: Difference Between Botox and Dysport?

In the realm of cosmetic neuromodulators, Dysport and Botox are two of the most popular brand-name injectables used to relax wrinkles and fine lines. Both products share the same primary active ingredient (botulinum toxin type A) and work by blocking muscle contractions to smooth the skin. However, they differ in formulation, dilution, diffusion, dosing, and approved uses. This comprehensive guide compares Dysport vs Botox, covering how they work, their pros and cons, cost and dosage, medical applications (including off-label uses), and more. By understanding these differences – from FDA approvals to “units” of dosage – you can better decide which treatment may suit your needs.

Figure: A medical professional administers a cosmetic Dysport or Botox injection to reduce forehead wrinkles.

Both Dysport® and Botox® are non-surgical wrinkle treatments that take effect in days and require minimal downtime. They temporarily relax targeted facial muscles, so expression lines (like frown lines and crow’s feet) become less visible. Despite their similarities, subtle differences mean one may be better suited than the other for certain areas or patients. In the sections below, we break down Dysport vs Botox side-by-side on key factors: how they diffuse, onset and duration of results, dosing and unit conversion, FDA approvals, cost, side effects, and special uses (e.g. for jaw masseter or medical conditions). We also touch on Xeomin, a third neuromodulator, to put the comparison in context. Wherever possible, we cite credible sources to back the information.

What Are Dysport and Botox?

Dysport and Botox are both brand names for botulinum toxin type A injections. This neurotoxin is derived from the bacterium Clostridium botulinum, and in tiny, controlled doses it blocks nerve signals to muscles, causing temporary muscle relaxation. By “freezing” overactive muscles, these injectables smooth out dynamic wrinkles – lines that appear with facial movements. For example, frown lines (between the eyebrows), crow’s feet (around the eyes), and forehead lines dysport vs botox

• Dysport (abobotulinumtoxinA) – FDA-approved for treating moderate to severe glabellar (frown) lines. Approved in 2009 for cosmetic use, it is specially formulated for wider diffusion. Dysport’s formula includes smaller protein complexes that tend to spread more after injection. This wide diffusion can be an advantage for larger treatment areas but may make it less precise in small areas.
• Botox (onabotulinumtoxinA) – FDA-approved for glabellar lines, forehead lines, and crow’s feet. Botox was the first cosmetic botulinum toxin approved (2002) and has a long track record. Its formulation contains a larger protein complex, which generally stays closer to the injection site. This can allow very precise dosing in delicate areas like around the eyes dysport vs botox

Despite these formulation differences, both smooth wrinkles in 3–7 days by preventing the targeted muscles from contracting. Results typically last 3–5 months for either treatment, though individual experiences vary. No surgery is needed, and recovery is minimal – most people resume normal activities immediately after injections, experiencing at most mild redness or bruising. Before choosing a product, consider the key differences below:

Dysport vs Botox: Key Differences

1. Formula and Diffusion

The main chemistry of both is botulinum toxin A, but trace proteins differ. Dysport’s toxin is formulated with smaller protein complexes, which tend to diffuse more widely once injected. In practice, this means:

• Dysport diffuses widely: It spreads into nearby muscles more readily. This can be useful when treating broader areas like the forehead. It may also produce a more natural, blended look across regions because adjacent muscles are partially relaxed. However, the wider spread also increases risk of affecting unintended muscles, potentially causing issues like mild eyelid droop if injected too close to the eyes.
• Botox stays localized: With a heavier protein complex, Botox tends to remain closer to the injection site. This allows for very precise targeting (e.g. specific facial lines or small areas). Botox is typically preferred for delicate areas (crow’s feet, bunny lines) where high precision is desired dysport vs botox

Expert Insights: The Cleveland Clinic notes that Dysport’s protein “allows it to diffuse further or spread more” compared to Botox. DermaBlue adds that Dysport’s smaller molecules may make it act a bit faster, while Botox’s precision suits smaller muscles dysport vs botox

2. Approved Uses and Treatment Areas

Both are FDA-approved for glabellar frown lines. The differences come in other areas:

• Botox: FDA-approved for forehead lines, crow’s feet (around eyes), and glabellar lines. It’s also used off-label in many face and neck areas. Its precise dosing makes it ideal for regions needing exact control (upper lip lines, chin dimpling, etc.).
• Dysport: FDA-approved only for moderate-to-severe glabellar lines. However, cosmetically, many injectors use Dysport in a wider range of areas too. Its tendency to cover more area with fewer injections makes it popular for foreheads and large frown areas dysport vs botox

Both can treat crow’s feet, but practitioners often prefer Botox there for precision. Dysport’s manufacturer recommends it for larger areas; many patients report Dysport is effective on forehead lines due to its spread.

Special uses: Both can be injected into the masseter muscles (jaw) to reduce teeth grinding or slim a square jaw. In that case, Dysport’s wider diffusion may ease injection across the large masseter, whereas Botox might require more injection points. Scientific guidance is limited, but one expert note: “Both Dysport and Botox offer excellent results for masseter treatments, but the choice depends on your specific goals and preferences.” (Sources suggest similar safety profiles.) dysport vs botox

3. Onset and Duration of Results

• Onset: Dysport often acts faster. Many patients see improvement in 2–3 days with Dysport. Botox typically takes a bit longer – 3–5 days for initial effects and up to two weeks for full result. For example, Cleveland Clinic notes Dysport’s effects appear in “about two days” on average, whereas Botox may take about a week. This faster onset can be a plus for patients wanting quick results, though it also means effects can taper earlier in some cases dysport vs botox
• Duration: Both last on the order of months. Most people enjoy smooth results around 3–4 months before needing touch-ups. Some studies and anecdotal reports suggest Botox can last a bit longer in some patients – up to 6 months in optimal areas. One practice notes that after a year of use, some patients find Botox “lasts longer because it takes less medicine to relax the muscles,” though this is anecdotal. Generally, expect to schedule repeat injections 3-4 times a year, regardless of product. The exact duration varies by muscle strength, metabolism, and dosage used dysport vs botox

4. Dosage and Units Conversion

Dysport and Botox use different unit measurements; they are not interchangeable by number. Roughly, 1 unit of Botox ≈ 3 units of Dysport. In practice, this means a given treatment will require more Dysport units (because it’s more dilute per unit) to achieve the same neuromuscular effect as Botox.

• Rule of Thumb: Clinicians often use a 1:3 conversion. For example, if you would use 20 units of Botox for a frown-line treatment, you would use about 60 units of Dysport. IAPAM confirms: “Patients average 20 units of Botox versus 40 units of Dysport” in typical treatment scenarios (note exact ratios can range from 1:2.5 to 1:4 depending on provider preference)dysport vs botox
• Concentration: Dysport is more dilute (per unit) than Botox. This aligns with how many units are needed for an effect. The Cleveland Clinic notes a recommended Dysport dose up to 50 units for glabellar lines, whereas typical Botox dosing for that area is ~20 units. Dermatologists and surgeons caution that overdose can occur if conversion isn’t done properly dysport vs botox

The key takeaway: You’ll use a higher unit count of Dysport, but each unit costs less, so overall cost can be comparable (see below). Always have a qualified provider calculate dosing for your specific treatment.

5. Cost Comparison

Prices vary by location and provider, but unit costs tend to differ:

• Botox per unit: Typically around $12–$16 per unit in the US.
• Dysport per unit: Typically around $4–$6 per unit.

However, because Dysport requires ~3× more units per area, the overall total cost per treatment is often similar. For example, one aesthetic doctor notes that although Dysport units are cheaper, the higher dosage needed makes total cost “six of one, half a dozen of the other”. Another review found average session costs of $300–$600 for Botox and about $400 for Dysport – in the same ballpark.

Cleveland Clinic reports the American Society of Plastic Surgeons’ averages: about $466 per session for either Botox or Dysport. Clinics may offer package deals or specials, so pricing can vary. Below are general trends:

• Dysport can appear cheaper per session (due to per-unit price), but remember you will need more units.
• Botox has a higher unit price but uses fewer units.
• Because of this, overall treatment cost is often comparable. Some find Dysport slightly less expensive, others find Botox cheaper depending on promotions dysport vs botox

When comparing, ask clinics for both unit prices and expected total units needed. Also consider long-term costs: if one product were to last significantly longer (often not the case), that could affect annual spending. Most experts agree cost differences should not be the only deciding factor; effectiveness and patient preference matter more dysport vs botox

6. Onset & Longevity: Scientific Notes

Clinical observations align with what we’ve described: Dysport’s smaller molecules may bind and diffuse quickly. The International Association for Physicians in Aesthetic Medicine (IAPAM) notes a typical onset of Dysport in ~24 hours, Botox in ~72 hours, and a bit slower for Xeomin (a third toxin) at ~4 days. Those numbers are averages: some people see Dysport effects in 1-2 days, Botox in 3-5 days dysport vs botox

As for how long they last, studies show both last 3-6 months when dosed appropriately. The DermaBlue clinic blog notes Botox “typically lasts 3 to 6 months” and most patients see best results re-injected every 3–4 months. Dysport usually falls in the same 3–6 month range. Individual metabolism and muscle usage speed up or slow down wear-off.

7. Side Effects and Safety

Both treatments are very safe when injected by qualified providers. Common side effects for either include: mild pain or redness at the injection site, swelling, or bruising. Temporary drooping (ptosis) of eyelids or eyebrows can occur if the toxin diffuses into nearby muscles – more likely if injected incorrectly, especially with Dysport’s wider spread dysport vs botox

No serious side effects are expected in cosmetic use. Rarely, systemic symptoms (like flu-like fatigue or toxin spread) have been reported, but these are exceedingly uncommon. FDA and dermatology guidelines emphasize choosing a board-certified injector to minimize risk. If you have neuromuscular disorders, are pregnant, or have allergies to components (see below), you should avoid these treatments dysport vs botox

One specific note: Dysport contains a small amount of lactose (milk protein) as a stabilizer, whereas Botox does not. If you have a severe milk allergy, mention it; your doctor might prefer Botox. Otherwise, both have excellent safety records in healthy adults dysport vs botox

Pros and Cons of Dysport vs Botox

Below is a quick bullet-point comparison of advantages and disadvantages for each:

• Pros of Dysport:
  • Faster onset: Often noticeable in 2–3 days.
  • Wider spread: Good for large areas (e.g. forehead, full glabella) and may give a natural, blended look.
  • Lower cost per unit: Leads to similar overall cost despite more units.
  • High safety profile: Extensively studied and FDA-approved since 2009.
  • May last as long or longer: Some reports suggest equal or slightly longer effect in some patients.
• Cons of Dysport:
  • Requires more units: Usually ~3× the number of units as Botox for equivalent effect.
  • Less precise: Wider diffusion can lead to unintended muscle relaxation (e.g. droopy eyelid) if not skillfully injected.
  • Not FDA-approved beyond glabella: Many uses are off-label (forehead, etc.).
  • Less common: Slightly fewer doctors have experience with it compared to Botox.
• Pros of Botox:
  • Extensive history: FDA-approved since 2002, used in cosmetics and medicine worldwide.
  • Precise effect: Narrower spread allows targeting small muscles (ideal for crow’s feet, fine lip lines).
  • Fewer units needed: Uses lower unit count for a given area.
  • Broad FDA approval: Approved for multiple facial areas (glabella, forehead, crow’s feet) and multiple medical conditions (migraines, hyperhidrosis, etc.).
  • Stable results: Well-researched for safety; some say consistent outcomes.
  • No lactose: Good choice if allergic to lactose (Dysport contains lactose).
• Cons of Botox:
  • Slower onset: Can take up to 5–7 days (even 10) to see effect.
  • Higher unit cost: Each Botox unit costs more, though fewer are needed.
  • Potentially less “natural” if overused: In unskilled hands, small muscles can be over-relaxed, causing unnatural looks (droopy brows).
  • Precision is double-edged: While good for small areas, achieving wide forehead coverage requires multiple injection points.

These lists are drawn from dermatologic practice and expert sources. Ultimately, the “best” choice depends on your anatomy and your injector’s experience dysport vs botox

Dysport vs Botox: How the Treatments Work

1. Consultation & Planning: A qualified provider examines your facial anatomy and discusses your goals (e.g. minimizing frown lines, evening brow). They’ll determine dose and injection sites.
2. Preparation: Skin is cleaned, and sometimes a topical anesthetic or ice is applied to ease discomfort. The actual injection is quick – a few tiny pricks with a fine needle.
3. Injection: Your provider injects Dysport or Botox into specific muscles. Dysport may be injected in a slightly broader pattern (to cover larger area), while Botox injections are more focal.
4. Onset:
   • Dysport: You may feel a difference within 2–3 days. Small lines begin to soften as the neurotoxin blocks nerve signals.
   • Botox: Expect initial improvement in 3–5 days, with full effect in up to 2 weeks.
5. Peak Effect: Both treatments typically reach maximum effect around 2–4 weeks post-injection. You’ll see wrinkles relax, giving a smoother appearance.
6. Duration: Results wear off as muscle function gradually returns. Expect to schedule follow-up injections about every 3–4 months to maintain results. Some people eventually stretch to 6 months between sessions.

During each session, follow your provider’s after-care instructions (e.g. avoid rubbing the area for a few hours). Mild side effects like redness, swelling or bruising are common and clear in a few days dysport vs botox

Dysport vs Botox vs Xeomin: The Trio of Neurotoxins

In addition to Botox and Dysport, Xeomin (incobotulinumtoxinA) is another FDA-approved botulinum toxin A option. While the question focuses on Dysport vs Botox, it’s useful to note how Xeomin compares:

• Xeomin (incobotulinumtoxinA): Marketed as a “naked” neurotoxin, it contains only the active toxin protein with no added complexing proteins. This means it has no accessory proteins; as a result, it’s less likely to trigger antibody formation (resistance) in very long-term use. Xeomin acts similarly to Botox in effect but tends to have an even slower onset (around 4 days). Unit for unit, Xeomin ≈ Botox (1:1 conversion), whereas Dysport:Botox is ~3:1. Xeomin and Botox are usually given in similar dosing (e.g. 20 units Xeomin for a glabella vs 20 units Botox, vs ~50-60 units Dysport). Cost per unit of Xeomin is in the $5-5.4 range, similar to Botox.
• Major differences: The IAPAM notes Xeomin has the longest shelf-life (no refrigeration needed) and the “cleanest” formulation. But for cosmetic patients, all three have similar outcomes when dosed properly. Dysport’s main distinction in the trio is its greater spread and lower unit cost dysport vs botox

Some FAQs around Xeomin:

• “Is Xeomin better than Botox?” Not universally; it’s another tool. Results are comparable to Botox for most patients, with a slight advantage in lower risk of antibodies.
• “Botox vs Dysport vs Xeomin?” All are effective neuromodulators. Your injector’s experience often dictates choice. Many providers also use Jeuveau (a newer formula) these days.

Dysport vs Botox Cost & Pricing

Comparing Costs: As noted, Dysport often has a lower per-unit price, but your total cost per treatment largely depends on how many units you need. Clinics may charge by unit or by area dysport vs botox

• Example: If Botox costs $14/unit and Dysport $4.50/unit, and you need 20 Botox units vs 60 Dysport units for glabellar lines, the session costs would be $280 vs $270 – nearly the same.
• Session Fees: Many practices quote a “per session” or “per area” price. Averages reported by ASPS/Cleveland Clinic are about $400–$500 per area, regardless of product. Seasonal promotions or package deals can affect these.
• Conversion Detail: For precise budgeting, remember the conversion: roughly 1:3 Dysport to Botox units. Also note that Dysport may require more frequent follow-ups if it wears off slightly sooner, which could factor in long-term cost.

Always ask: “What is your price per unit, and how many units will I need?” for both products. This will clarify the real cost comparison. And remember to budget for maintenance: full wrinkles treatments often mean 4 treatments per year.

Before & After: Results of Dysport vs Botox

Both treatments aim for natural-looking rejuvenation. Here are general observations:

• Before treatment: Dynamic wrinkles (visible when you move your face) are usually present and may begin to be visible at rest.
• After Dysport/Botox: Within a few days to a week, treated areas soften significantly. Vertical frown lines flatten, forehead lines weaken, and crow’s feet diminish. The face often appears more relaxed and “open-eyed.” Results should not look “frozen” if dosed properly; the goal is reduction of lines, not elimination of facial expression dysport vs botox

No two people look identical, but clinical photos (before/after galleries) of Dysport and Botox-treated patients show similar outcomes: fewer wrinkles in the targeted zones. One subtle difference reported anecdotally is that Dysport’s effect can “spread” so the transition from treated to untreated skin is very smooth over a wider area. Botox, being more focal, may leave sharper borders (though a skilled injector avoids noticeable edges for both).

We couldn’t include real patient images here, but many providers display before & after galleries on their websites. (For SEO: search “Dysport vs Botox before after images” to see examples). Remember, individual results vary. The provider’s skill is as crucial as the product choice for achieving desirable before/after outcomes.

Dysport vs Botox for Jaw (Masseter) Treatment

Using neuromodulators to slim the lower face (by injecting the masseter muscle) or to relieve TMJ pain is popular. Both Dysport and Botox can be used for masseter reduction. Key points of dysport vs botox

• Masseter muscle: a large chewing muscle in the jaw. Injections here reduce muscle bulk over months, slimming a square jawline. Also eases teeth-grinding/clenching.
• Product choice: Since masseters are large, Dysport’s wide diffusion can cover more of the muscle per injection, which some practitioners prefer. Botox, with its concentrated form, may require more injections to cover the entire masseter muscle. However, many providers use whichever product they are trained in.
• Units: Typical Botox masseter treatments might be ~20-30 units per side. Dysport would be roughly triple (60-90 units per side) for similar effect. Both last 4-6 months, and you typically repeat 2–3 times per year.

Scientific comparisons of “Dysport vs Botox for masseter” are limited. In general, outcome and safety are similar; choice often depends on injector experience. If you have a concern (e.g. migraines or TMJ), ask your doctor if one product is preferred. Otherwise, the differences mirror cosmetic use: Dysport may give a broader relaxation, Botox a more pinpoint effect dysport vs botox

Clinical Applications and Off-label Uses

While mainly known for wrinkle reduction, both have important medical uses:

• Botox: Widely used for chronic migraine prevention, muscle spasticity, eyelid spasms (blepharospasm), cervical dystonia, hyperhidrosis (excessive sweating), overactive bladder, and more. It is FDA-approved for many of these. In fact, Botox was first approved for eye muscle disorders in the 1980s, long before cosmetic use. Many medical insurance plans cover Botox for these conditions when prescribed by a specialist.
• Dysport: FDA-approved for cervical dystonia (neck spasms). Outside aesthetics, it’s often used (off-label) similarly to Botox for leg spasticity (e.g. post-stroke, cerebral palsy), migraines, and other dystonias. Some neurologists prefer Dysport for certain spasticity cases dysport vs botox

Both are used off-label in pain conditions like TMJ or masseter grinding. The effects on muscles are fundamentally the same, but dosing and injection patterns will differ for each use.

When comparing Dysport vs Botox for medical uses, remember the conversion ratio (1:3). For example, studies often use 300 Dysport units for chronic migraines (vs ~100 Botox units). Both have good safety profiles in medical contexts, though exact usage guidelines depend on the condition.

FAQs (Frequently Asked Questions)

Q1: What is Dysport vs Botox?
A: Dysport and Botox are brand names for injectable cosmetic treatments made from botulinum toxin type A. They temporarily relax facial muscles to reduce wrinkles. Dysport diffuses more and acts faster; Botox is more localized. Both are effective for wrinkles, with the choice often based on area and provider preference.

Q2: Are Dysport and Botox the same thing?
A: No, they are different brands/formulations of the same neurotoxin. They contain the same active ingredient but have different protein complexes and dosing. You cannot directly substitute unit-for-unit between them. Roughly 1 Botox unit ≈ 3 Dysport units.

Q3: Which lasts longer: Dysport or Botox?
A: In general, the duration is similar (3–6 months) for both. Some patients feel Dysport wears off slightly sooner, others feel Botox does. Clinical studies show comparable efficacy when dosed correctly. Duration depends on factors like dose, treated area, and metabolism.

Q4: How much does Dysport vs Botox cost?
A: Pricing varies, but expect similar total costs. Dysport units cost less (roughly $3–6 per unit) vs Botox ($12–16/unit). Because Dysport needs ~3× more units, overall treatment price often evens out. Average per-session costs (for one facial area) are typically in the $300–$600 range for either. Ask your clinic for a per-unit price and estimated total units.

Q5: How many units of Dysport vs Botox do I need?
A: It depends on area and severity of wrinkles. As a guide, practitioners use about 20 units of Botox or 60 units of Dysport for glabellar lines. For crow’s feet, about 12 Botox units per side (≈36 Dysport units per side). Forehead lines might need 10–30 Botox (30–90 Dysport). Always consult a provider – they will determine units needed for your facial anatomy.

Q6: Can I switch between Dysport and Botox?
A: Yes, you can switch. Many people try both products at different times. Just ensure you wait until the first wears off (typically 3-4 months) before trying the other. The conversion ratio should be applied when switching doses. Discuss with your doctor if switching is appropriate.

Q7: What about before and after results?
A: Both Dysport and Botox smooth wrinkles in treated areas. “Before and after” photos show similar outcomes: softened frown lines, fewer forehead creases, reduced crow’s feet. Neither causes a completely expressionless face if done correctly; you should still be able to move your face naturally. Results are gradual – see improvement over the first 1–2 weeks, then maintain for months. (Tip: Many clinics post galleries of their own patients online for visual reference.)

Q8: Which is better for masseter (jaw) treatment?
A: Both work for jaw slimming or teeth-grinding. Dysport’s broad spread can be handy for the large masseter muscle, potentially requiring fewer injections. Botox allows for very targeted dosing. The “better” choice depends on your specific case and your injector’s experience. Both can relieve jaw tension and slim the face when injected into the masseters.

Q9: Any alternative neuromodulators to consider?
A: Other FDA-approved options include Xeomin and Jeuveau, which are similar to Botox in use. Xeomin has no accessory proteins (so it’s “purer”). Jeuveau is newer but works like Botox. All have comparable effects on wrinkles. Choice of these newer brands often comes down to doctor preference or cost specials.

Q10: Is Dysport or Botox more painful?
A: Both injections use very fine needles. Most patients report only minimal discomfort with either. Injection pain is generally mild and brief. Dysport’s slightly more diluted formula may feel a little different, but there is no significant difference in pain level. Many clinics offer numbing creams or ice to make the procedure more comfortable.

Sources: Cleveland Clinic, Healthline, clinical reviews, and aesthetic medicine resources.

Conclusion

In summary, Dysport vs Botox are both excellent anti-wrinkle treatments made from botulinum toxin A. Dysport acts a bit faster and spreads over a wider area; Botox is more precise and has broader FDA-approved uses. Neither is objectively “better” overall – the best choice depends on your treatment area, goals, and medical history. Consult a board-certified injector (dermatologist or plastic surgeon) to discuss your specific needs. They can explain how many units you’ll need (Dysport units vs Botox units) and what results to expect.

Whether you choose Dysport or Botox, properly performed injections are generally safe and yield smoother, younger-looking skin for several months. Remember to factor in cost (unit price and number of units), onset time, and your comfort with either brand.

Have more questions about Dysport vs Botox? Share your concerns below or schedule a professional consultation.

Enjoyed this comparison? Feel free to share this article on social media or leave your own experiences in the comments. Your insights help others make informed choices about wrinkle treatments!